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News from 2009

GAMC Participates in SAMMPRIS
GLENDALE, CALIFORNIA * June 23, 2009 *
Glendale Adventist Medical Center recently announced that it is participating in a very important clinical trial for stroke called SAMMPRIS. The clinical trial looks at Stenting vs. Aggressive Medical Management for Preventing Recurrent events in Intracranial Stenosis. This is a National Institutes of Health funded multi-center trial.

The SAMMPRIS study compares the safety and effectiveness of either Intensive Medical Therapy PLUS Stenting or Intensive Medical Therapy alone to prevent stroke, heart attack or death in patients with narrowed brain blood vessels. The best treatment for prevention of another stroke or TIA in patients with narrowing of one of the arteries in the brain is uncertain.

A common treatment is the use of anti-clotting medications to prevent blood clots from forming in the narrowed vessel. There are a variety of medicines used for this purpose, including aspirin and clopidogrel (plavix). These medications are usually taken for the rest of a patients life.

However, a treatment that has been used successfully together with anti-clotting medications in patients with narrowing of the blood vessels of the heart is now being studied in the blood vessels of the brain. This treatment is called stenting.

Research has indicated a benefit in prevention of recurring stroke by Intensive Medical Therapy, which is treating risk factors for stroke like high blood pressure and elevated LDL (low density lipids the bad form of cholesterol).
The study will enroll patients over a 5 year period. Each participant will be involved in the study for a minimum of 1 year and a maximum of 3 years.

There are sixty medical centers in the United States participating in this study. All of these medical centers report to the Clinical Coordinating Center, which is located at the Medical University of South Carolina, and the Statistical Coordinating Center at Emory University. A total of 764 patients will be enrolled in the study nationwide.
Glendale Adventist Medical Center enrolled its first patient in the study just two weeks ago.

For more information on the study, visit